My main interest is in activity-dependent regulation of neural circuits combining functional approaches using electrophysiology and in vivo imaging with in-depth molecular analysis to reveal environmental regulators of development. My lab mainly, but not exclusively, uses the model of ocular dominance plasticity in the visual cortex. My studies are focused on the role of perineuronal nets and mechanisms controlling experience-dependent gene-expression at transcriptional (epigenetic modifications) and post-transcriptional (microRNAs) level. I also study these mechanisms in the context of neurodevelopmental disorders studying disease models of MeCP2, CDKL5 and Slc6a8 deficiency.