Investigating the development and the maturation of cerebral cortex neuronal networks derived from hiPScs, focusing on the contribution of inhibitory neurons to the plasticity and the performance of the networks in assays of synaptic potentiation. This activity is crucial to understanding the contribution of the GABAergic inhibition in the formation of healthy cortical networks and its involvement in distinct neuro-diseases such as epilepsy, schizophrenia, cognitive and depressive disorders.